Chibi-Usa gets sucked into the far reaches of space-time and vanishes! It's up to Tuxedo Mask to reach her and get her back safely while Sailor Moon and the others must escape Nemesis and the evil clutches of Wiseman and his cronies. But as Tuxedo Mask travels through the space-time storm, he encounters an ominous woman claiming to be his daughter! Who is this strange woman? Is she really Chibi-Usa?!

"Old friends and new enemies lurk in the mysteries surrounding Mugen Academe. The Death Busters crave the Hoste, the human energies, of Sailor Moon and her friends -- and they'll prey on the girls' dreams and weaknesses to get it! Furthermore, prophetic dreams hint of 'talismans' that could awaken a 'Deity of Destruction.' Could these things be connected to the guardians' power? And are the Sailor Senshi capable of murdering the innocent to save the...

Just when Usagi thinks things are getting back to normal, she finds that Mamoru is leaving to study abroad in America and Chibi-Usa is returning to the thirtieth century.